Power system stabilizer (PSS) is an important equipment to increase damping and suppress low frequency oscillations of power system. According to the grid operation code (GB/T 31464—2015), the excitation system of thermal-, nuclear- and gas-power generating units (100 MW and above) must have PSS ability. The time constant of lead-lag compensator needs to be configured during PSS test. At present, configuration methods for parameters are inefficient and need to be optimized. In order to solve this problem, automatic configuration method for PSS parameters based on MATLAB simulation is proposed. By setting the expected phase value at each frequency and constructing the objective function with the sum of squares of phase differences, the automatic calculation of PSS parameters under specific phase requirements at each frequency can be realized. The steps of this method are given in detail, and the method is verified on an 1 000 MW thermal-power generating unit during the PSS test.