Taking the multi-motor synchronization control of computer numerical control machine tool servo drive system as the research object, a synchronization control strategy based on multi alternating current servo motors is proposed. This strategy combines a virtual spindle and a deviation-coupled synchronous control approach with back propagation neural network proportional integral derivative control as well as adaptive robust control. The system operation state is simulated by building a Matlab/Simulink simulation platform. The simulation results show that the proposed synchronous control strategy has good synchronous performance and servo effect, and shows superiority in improving the control accuracy and response speed of the multi-motor linkage system, reducing the influence of friction and backlash, and enhancing the robustness of the system.